Aloe Interview Series:
Part #
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#72 "Secrete
Benefits of Aloe" ~ Scott Siegel
Articles
Aloe is more healthful than thought
~ Dr Siegel, MD formerly of
Dallas, now retired, helped pioneer the use of Aloe in its
most effective form for rejuvenation, disease prevention,
regaining ones health ~ in most circumstances: alleviating
pain. Why does the US army want Aloe? Why does it
heal? Do you want the Whole leaf? the gel or the liquid and
Why? Dr Siegel's son, Scott, explains the history of
Aloe, explores these questions and more, in the first of
many on this amazing gift from God.
1-800-807-4779
#75
"Secrete Benefits of Aloe" ~
Scott Siegel
Articles
Aloe restores the bodies
ability to communicate, so it will know a friendly from a
foe and eliminate it. Stop viruses from getting a foot
hold in the body. Aloe will help perform many
functions:
*
Restoration- helps body adapt to stress
* Recognition- identifies problems in the body
* Repair- cleans away damaged tissue
* Regeneration- cell production is corrected
This talk is
about recognition and communicating problems -
1-800-807-4779
by
Dr. R. Siegel M.D.
The
Science & Regulation of Immunity
Our body has an innate capacity to defend and heal
itself. We are now in an age for understanding the inborn,
self-regulating, natural ability of our immune system. Much
as the earlier clinician examined the body with external
stethoscope and otoscope, today we use the modern tools of
the biochemical/molecular laboratory to exam the inner
conditions of the body. Armed with high tech electron and
photon microscopes for instance, we study specially stained
cross tissue for cellular changes. Coordinated with clinical
observation and the process for cellular and humoral
integration and healing.
In a summary paper by bio-pathologist Dr. Reg McDaniel
MD, a highly coordinated sequence of immune events can be
traced: recognizing the flow of macrophage activation, an
army of efficient immune molecules, T and B elements,
cytokine immune messengers, gene activation, response of
protein synthesis and cellular remodeling and appropriate
feedback loops such a reset and gene suppression. Notable is
the role of the large immune supervisor- the monocyte/macrophage,
or M/Ms-which wanders through the extracellular fluids,
constantly monitoring [touching, feeling] the condition of
tissues for organ damage, infection, malignancy, and aging.
The history of M/Ms date back to the early 1800's, when
Behring discovered humoral substances in serum capable of
defense, eventually to be studied as antibodies, complements
and acute reactive-phase proteins. He saw a blend of immune
agents that protected animals from disease by deactivating
the toxins of bacteria. Later experiments by Metchnikoff
showed the role of leukocytes, engulfing and destroying
microscopic organisms. It was then recognized that both
humoral [chemical] molecules and immune cells mediate the
host defense.
William Cooley in 1891 cured soft tissue malignant
sarcomas, using an anti-tumor fraction akin to what we see
today as toxic shock. His particular toxin- a polysaccharide
released from bacterial membranes- proved too toxic for
human treatment. An idea was born. Particular
polysaccharides serving as a major sponsor can trigger a
cascade of immune-inflammation that even cures tumors.
Recently, it has been discovered that an analogous molecule,
the plant molecule of beta-polysaccharide, can act as a
critical precursor of immunity: triggering the macrophage
that, in turn, both calls out the army of the immune system
and in addition, safely orchestrates the over all defense of
the body.
A vast array of humoral chemicals and cells respond to
the macrophage. That is, the giant macrophage, much like a
five star General Patton, orchestrates and modulates the
various elements of the immune system. These types of immune
"troops" recognized today include helper and suppresser
killer antibody types of T and B cells, humoral chemicals
such as leukocytes [within the ground regulatory system] to
initiate the defense activities of phagocytosis, lysosomal
enzymes, cytolysis, etc. In turn, cytokine messenger
molecules "talk" to membrane receptors of the host cells
which then send secondary signals into the particular
proteins needed to defend and to repair dysfunctional
tissue. Moreover, the host genes can even program a
remodeling of the membranes of attack cells, defeating their
attempts, for instance to dock with immune CD's.
The most recent laboratory findings demonstrate that it
is the core molecular sequence of the mannan component of
cell membrane structures that serves as a first level signal
to stimulate the release of M/Ms, both in animal and human
cell lines and that these giant macrophages serve in turn as
the primal surveyor and coordinator, of the total dynamic
immune process. Extensive reviews of pharmaceutical research
show the initial effects of M/Ms, to target, induce and
modulate over 100 cell activities and cytokines, including
enhanced production, in a dose-related manner, of
interleukin-1 [IL-1] prostaglandin E-2 [PGE-2] lymphocyte
CD4, natural killer and CD8 lymphocytes, Staphylococcal
phagocytosis and tumor cell destruction.
The Regulation of Immunity
An M/M command cell [monomacrophage] emerges from the
sinuses of the spleen, liver and bone marrow to circulate
and migrate into tissues or organ cavities. They locate in
greater numbers in the skin, mucosa, and other strategic
portals of common invasion. The M/Ms technique is to analyze
structures on the cell surface [oligosaccharides chains of
glycoprotein] to differentiate cells of Self, non-Self or
damaged/altered Self. The M/ Ms are triggered into
activation if they recognize a critical sequence of the
membrane saccharides as being an abnormal non-Self or
damaged/altered Self. If so, they audit ongoing multiple
cellular mechanisms which sense and induce enzymes to
destroy the "errors" [such as assembly errors in
glycosylation] by targeting signals of IL-1, 54, INF-G, 55,
and RNF etc. Assayed by ELISA techniques, M/Ms induce
production on a concentration gradient basis of PG-E2 24,
IL-1B, IL-2, IL-6, THF-alpha, GM-CSF, I~F-alpha and
INF-Gamma 57, are shown to modulate defense and repair, and
are sensitive to the simultaneous time/zone/sequence needs
of tissue.
Mannose polymers produce a dose dependent increase of
cell proliferation in culture medium. The hydrolased
cleaved mannose units [ex. the Mannose molecule] enhance
cell growth of human stromal fibroblasts and parenchyma
cells of cat kidney. Also, it alerts genetic alteration of
the structural membrane envelope of an attack virus,
obstructing the chance for viral host cell docking. The
enhanced growth of human stromal fibroblasts suggests that
the ground regulatory system serves as the initial action
site/vehicle of induced immune behavior. To sum, biological
functions are mediated by the advanced macrophage that in
turn can be stimulated by the polymannan molecule. Mannose
molecules are components of the surface membranes of cells
and are responsible for essential complex biochemical
activities of cell life. The molecular structure of the
cellular membrane in plants and animals is synthesized upon
a core of mannose molecules. It is a gene dictated
saccharides that ultimately can be read as cell signature
and can be selectively responded, immunologically.
Mannan serves as a universal agent for stimulating the
macrophage and in turn, the immune system. Its functions are
essential for good health and defense. The
beta-mannose-6-P04 of plant cell origin is a relatively
nontoxic analogue of the [toxic] bacterial cell membrane
first used by Dr. Cooley. The functional polymannan
represents the first safe molecule in the new scientific
field known as Glycobiology or Glycoscience. It meets the
standards imposed by new government legislation, classified
as Nutraceutical.
Mannans are relatively rare in common western diets. The
body has a critical conservation of metabolic, low molecular
weight mannans. Specific transport molecules [mannose
binding proteins MBP] are produced in the liver of higher
order animals. Research on the polymannan molecule supported
scientifically by over $70 million in research studies, is
the only functional molecule of Aloe. Aloe Immune TM
is organically grown aloe and with a very unique
dehydration process to retain all four chains of molecular
weight polymannans found in aloe. Independent Labs have
shown Aloe Immune TM aloe to
have higher concentrations of the largest molecular weight
polymannans, Acemannan (Barbadensis Miller species) to have
over 1,000,000 - 5,000,000 Daltons.
The polymannan molecule commands the position of
Nutraceutical health care, acting to orchestrate [upgrade
and downgrade] the immune modulation process. It enhances
the host defense against a broad array of biological immune
assaults, including allergy and hypersensitivity,
auto-immune diseases, wound healing, induction of necrosis
in malignant tumors and micro viral and bacterial
infections. The pharmaceutical grade ACE-Mannan has been
proven for safety and is accepted by the USDA for animal
treatment of tumors and by the FDA for oral and skin
treatment in humans. Currently controlled research is in
process, per the FDA protocol for treatment of twenty types
of human cancer and digestive ulceration disease.
source: www.4rhealthproducts.com